Cheung Yat Kin just graduated and is prepared to practice neurosurgery. He takes his work seriously and strictly follows the rules. His group of medical interns respects him just as much as they fear him. Kin wanted to fulfil his younger brother Cheung Yat Hong's wish to study medicine overseas, suffering from a pair of paralyzed legs. Kin worked hard and concentrated on his job in order to save enough money and did not think about relationships at all until he met Fan Chi Yu. Once Yu became a famous doctor, she had a major devotion to medicine and adored Kin. Therefore, she did not mind taking the initiative to pursue him. One day, Hong's condition unexpectedly worsens, and he dies. Kin found himself lost in life, and his interns were greatly influenced by his feelings, including Yeung Pui Chung, who Kin had always viewed as a brother and Yu's younger sister Fan Mei Suet. At Kin's toughest time in life, he suddenly learns Yu suffers from a severe illness, which may become a life-threatening situation. Yu had been active in searching for treatment, and her persistent spirit brought Kin back on his feet to support her. Unfortunately, Yu's treatments failed several times, and eventually, the only opportunity she had was to advance in a dangerous surgery. As a doctor, Kin supports Yu in taking on this surgery, but as her boyfriend, he feels uneasy...